Analysis of Blood Biochemical Profiles in Elderly Women for Screening Dementia Diagnostic

Exploring Blood Biochemical Profiles for Dementia Screening in Elderly Women: A Collaborative Nursing Research

Dementia remains a major health challenge worldwide, particularly among elderly women. Beyond the well-known biomarker beta-amyloid, recent research suggests other biochemical markers may help improve early diagnosis and monitoring.

A team of researchers including Dr. Nita Fitria, S.Kp., M.Kes., AIFO., from the Faculty of Nursing, Universitas Padjadjaran (Unpad), alongside experts from the Indonesia University of Education, Adhirajasa Reswara Sanjaya University, and Santo Borromeus University, conducted a cross-sectional study comparing blood biochemical profiles of elderly women with and without dementia.

Using advanced techniques such as High-Performance Liquid Chromatography (HPLC) and ELISA, the study found significant differences in plasma levels of amyloid beta-42 (Aβ42), acetylcholinesterase (AChE), brain-derived neurotrophic factor (BDNF), and superoxide dismutase (SOD). These findings highlight promising additional biomarkers for dementia screening beyond Aβ42 alone.

This research contributes toward Sustainable Development Goal 3 (Good Health and Well-being) by advancing early detection strategies critical for improving dementia care and patient outcomes.

🔗 Read the full article: https://doi.org/10.47836/mjmhs.21.s3.13