Padjadjaran University Research Advances Green Dentistry with Biosynthesized Nanoparticles for Oral Cancer Treatment
A systematic review led by Faris Hernando Reviansyah and colleagues from Universitas Padjadjaran’s Faculty of Dentistry and Faculty of Nursing explores the promising role of biosynthesized superparamagnetic iron oxide nanoparticles (SPIONs) derived from agricultural waste in oral cancer therapy.
Oral cancer remains a global health challenge with rising incidence and high mortality rates. Traditional treatments like chemotherapy and surgery face limitations due to toxicity and low tumor specificity. This study highlights an innovative “green dentistry” approach, where lignin from paddy agricultural waste is used to biosynthesize SPIONs, combining eco-friendly synthesis with cutting-edge cancer therapy. SPIONs serve dual functions as drug delivery vehicles and hyperthermia agents when exposed to magnetic fields, potentially increasing treatment efficacy while minimizing side effects on healthy tissues.
This research supports Sustainable Development Goals by improving health outcomes (SDG 3: Good Health and Well-being) through enhanced cancer treatment efficacy and patient quality of life, while also promoting responsible consumption and production (SDG 12) by utilizing agricultural waste in nanoparticle synthesis, demonstrating how sustainable innovations can drive progress in healthcare and environmental stewardship.
🔗 Full Article: https://doi.org/10.2147/CMAR.S477791
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